HESI RN
Biology Practice Test
1. What is the most significant contributor to cellular function?
- A. Proteins
- B. Phospholipids
- C. Carbohydrates
- D. Fatty acids
Correct answer: A
Rationale: The correct answer is A: Proteins. Proteins are the most significant contributor to cellular function as they play crucial roles in almost all biological processes. They act as enzymes that catalyze reactions, are involved in cell signaling pathways, and provide structural support to cells. Phospholipids (Choice B), while important for cell membrane structure, do not have the same diverse functions as proteins in cellular processes. Carbohydrates (Choice C) primarily serve as an energy source and structural components but are not as versatile in cellular functions as proteins. Fatty acids (Choice D) are essential components of cell membranes and energy storage molecules but do not have the same broad range of functions as proteins in cellular processes.
2. Water is a polar molecule that can be:
- A. cohesive and corrosive
- B. cohesive and adhesive
- C. electrostatic and ionic
- D. repellent and attractive
Correct answer: B
Rationale: Water is a polar molecule due to an uneven distribution of electrons, allowing it to form hydrogen bonds. This property makes water both cohesive (attracted to itself) and adhesive (attracted to other substances). Choice A is incorrect because water is not corrosive; rather, it is a solvent. Choices C and D are incorrect as they do not describe the cohesive and adhesive properties of water.
3. During which stage of mitosis do the chromosomes gather on either side of the separating cell?
- A. Metaphase
- B. Telophase
- C. Anaphase
- D. Prophase
Correct answer: B
Rationale: The correct answer is B, Telophase. During telophase, the chromosomes gather at opposite poles of the cell as the nuclear envelopes start to form around them, indicating the end of cell division. Choices A, C, and D are incorrect because during metaphase, the chromosomes align in the middle of the cell; in anaphase, the chromosomes separate and move towards opposite poles; and in prophase, the chromosomes condense and the nuclear envelope breaks down, respectively.
4. What is located on the rough endoplasmic reticulum?
- A. Microvilli
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: D
Rationale: The rough endoplasmic reticulum is studded with ribosomes, which are responsible for protein synthesis. Ribosomes are the correct answer because they are the organelles directly associated with the rough endoplasmic reticulum. Microvilli (choice A), mitochondria (choice B), and lysosomes (choice C) are not typically located on the rough endoplasmic reticulum. Microvilli are found on the surface of cells to increase surface area, mitochondria are the powerhouses of the cell responsible for energy production, and lysosomes are membrane-bound organelles containing digestive enzymes.
5. In DNA, the nucleotide base adenine always binds with which of the following?
- A. Guanine
- B. Uracil
- C. Thymine
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Thymine. In DNA, adenine always pairs with thymine, forming a base pair held together by hydrogen bonds. Guanine pairs with cytosine. Uracil is found in RNA, not DNA. Cytosine pairs with guanine. Therefore, option C is the correct pairing for adenine in DNA.
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