Nursing Elites

1. The term pleiotropy is best defined as which of the following?

• A. A situation in which one gene remains unexpressed
• B. One gene influencing multiple, seemingly unrelated phenotypic traits
• C. Two genes affected by a single allele
• D. A condition in which multiple genes are missing

Correct answer: B

Rationale: Pleiotropy is best defined as one gene influencing multiple, seemingly unrelated phenotypic traits. This phenomenon showcases the multifunctionality of genes, where a single gene can have effects on various aspects of an organism's phenotype. Choices A, C, and D do not accurately capture the concept of pleiotropy. Option A refers to gene expression, not pleiotropy. Option C describes genetic interactions but not in the context of pleiotropy. Option D talks about missing genes, which is unrelated to the definition of pleiotropy.

2. In meiosis, the chromosome number is reduced from:

• A. 46 to 23
• B. 46 to 33
• C. 28 to 14
• D. 24 to 12

Correct answer: A

Rationale: The correct answer is A: "46 to 23." In meiosis, the chromosome number is reduced by half to form gametes for sexual reproduction. In humans, where the diploid chromosome number is 46, meiosis results in haploid cells with 23 chromosomes. Choices B, C, and D are incorrect because they do not represent the correct reduction in chromosome number during meiosis.

3. What is the most significant contributor to cellular function?

• A. Proteins
• B. Phospholipids
• C. Carbohydrates
• D. Fatty acids

Correct answer: A

Rationale: The correct answer is A: Proteins. Proteins are the most significant contributor to cellular function as they play crucial roles in almost all biological processes. They act as enzymes that catalyze reactions, are involved in cell signaling pathways, and provide structural support to cells. Phospholipids (Choice B), while important for cell membrane structure, do not have the same diverse functions as proteins in cellular processes. Carbohydrates (Choice C) primarily serve as an energy source and structural components but are not as versatile in cellular functions as proteins. Fatty acids (Choice D) are essential components of cell membranes and energy storage molecules but do not have the same broad range of functions as proteins in cellular processes.

4. Which of the following correctly identifies the two types of cells?

• A. Mitosis and meiosis
• B. Mitochondrion and chloroplast
• C. Genotype and phenotype
• D. Prokaryotic and eukaryotic

Correct answer: D

Rationale: The correct answer is D: Prokaryotic and eukaryotic. Cells are classified into two major types: prokaryotic, which lack a nucleus, and eukaryotic, which have a defined nucleus and other membrane-bound organelles. Choice A, mitosis and meiosis, refers to cell division processes. Choice B, mitochondrion and chloroplast, are cell organelles involved in energy production and photosynthesis, respectively. Choice C, genotype and phenotype, relate to genetic characteristics and physical traits, not cell types.

5. During which stage of mitosis does the nuclear envelope begin to disappear and the chromosomes start attaching to the spindle forming along the cell's axis?

• A. Prometaphase
• B. Metaphase
• C. Anaphase
• D. Prophase

Correct answer: A

Rationale: The correct answer is A, Prometaphase. During prometaphase, the nuclear envelope disintegrates, and chromosomes start attaching to spindle fibers. In metaphase, chromosomes align in the middle of the cell. Anaphase is characterized by the separation of sister chromatids, and prophase involves the condensation of chromosomes and the beginning of spindle formation.

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