HESI RN
Biology Practice Test
1. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
2. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
3. The cellular membrane contributes to all except which of the following?
- A. Cell energy production
- B. Cell permeability
- C. Cell communication
- D. Cell protection
Correct answer: A
Rationale: The cellular membrane is involved in regulating cell permeability, communication, and protection. However, it is not directly involved in energy production. Choice A is the correct answer because the cellular membrane does not produce energy; instead, it regulates the passage of molecules in and out of the cell. Choices B, C, and D are incorrect because the cell membrane plays key roles in controlling what enters and exits the cell, facilitating communication between cells, and providing structural support and protection to the cell.
4. Which of the following is the process that reduces cells originally classified as diploid to haploid?
- A. Meiosis
- B. Photosynthesis
- C. Mitosis
- D. Cytokinesis
Correct answer: A
Rationale: The correct answer is A, Meiosis. Meiosis is the cell division process that reduces the chromosome number from diploid to haploid, which is essential for sexual reproduction. Choice B, Photosynthesis, is the process by which green plants and some other organisms use sunlight to synthesize foods with the help of chlorophyll. Choice C, Mitosis, is a cell division process that results in two diploid daughter cells with the same number of chromosomes as the parent cell. Choice D, Cytokinesis, is the division of the cytoplasm following cell division.
5. Which of the following is a group of three RNA nucleotides?
- A. A stop codon
- B. A codon
- C. An anticodon
- D. tRNA
Correct answer: B
Rationale: The correct answer is B - A codon. A codon is a sequence of three RNA nucleotides that specifies a particular amino acid or a stop signal during protein synthesis. Choice A, a stop codon, is a sequence of three nucleotides that signals the termination of protein synthesis. Choice C, an anticodon, is a group of three nucleotides found in tRNA that pairs with the complementary codon in mRNA. Choice D, tRNA, stands for transfer RNA, which is a type of RNA that carries amino acids to the ribosome during protein synthesis.
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