HESI RN
HESI Medical Surgical Practice Quiz
1. The patient will take a high dose of azithromycin after discharge from the hospital. Which statement by the patient indicates understanding of the teaching?
- A. I may take antacids 2 hours before taking this drug.
 - B. I should take acetaminophen for fever or mild pain.
 - C. I should expect diarrhea to be a common, mild side effect.
 - D. I should avoid dairy products while taking this drug.
 
Correct answer: A
Rationale: The correct answer is A. Azithromycin peak levels may be reduced by antacids when taken at the same time, so patients should be cautioned to take antacids 2 hours before or 2 hours after taking the drug. Choice B is incorrect because high-dose azithromycin carries a risk for hepatotoxicity when taken with other potentially hepatotoxic drugs such as acetaminophen. Choice C is incorrect as diarrhea may indicate pseudomembranous colitis and should be reported, not expected as a common mild side effect. Choice D is incorrect; there is no restriction for dairy products while taking azithromycin.
2. A nurse cares for a client with urinary incontinence. The client states, “I am so embarrassed. My bladder leaks like a young child’s bladder.” How should the nurse respond?
- A. I understand how you feel. I would be mortified.
 - B. Incontinence pads will minimize leaks in public.
 - C. I can teach you strategies to help control your incontinence.
 - D. More women experience incontinence than you might think.
 
Correct answer: C
Rationale: The nurse should accept and acknowledge the client’s concerns, and assist the client to learn techniques that will allow control of urinary incontinence. The nurse should not diminish the client’s concerns with the use of pads or stating statistics about the occurrence of incontinence.
3. The nurse is caring for a patient who has recurrent urinary tract infections. The patient’s current infection is not responding to an antibiotic that has been used successfully several times in the past. The nurse understands that this is most likely due to
- A. acquired bacterial resistance.
 - B. cross-resistance.
 - C. inherent bacterial resistance.
 - D. transferred resistance.
 
Correct answer: A
Rationale: The correct answer is A: acquired bacterial resistance. Acquired resistance happens when an organism has been exposed to the antibacterial drug, making it less effective over time. Cross-resistance (B) occurs when resistance to one drug leads to resistance to another. Inherent resistance (C) happens without prior exposure to the drug, meaning the bacteria are naturally resistant. Transferred resistance (D) involves the transfer of resistant genes from one organism to another, contributing to resistance development.
4. A client is tested for HIV with the use of an enzyme-linked immunosorbent assay (ELISA), and the test result is positive. The nurse should tell the client that:
- A. HIV infection has been confirmed
 - B. The client probably has an opportunistic infection
 - C. The test will need to be confirmed with the use of a Western blot
 - D. A positive test is a normal result and does not mean that the client is infected with HIV
 
Correct answer: C
Rationale: When an ELISA test for HIV is positive, it is essential to confirm the result with a Western blot. The Western blot is the confirmatory test for HIV. Choice A is incorrect because a positive ELISA test does not confirm HIV infection. Choice B is incorrect as it assumes a different diagnosis. Choice D is incorrect because a positive ELISA test does indicate potential HIV infection and requires confirmation.
5. Why is the combination drug trimethoprim-sulfamethoxazole (TMP-SMX) necessary?
- A. To broaden the antibacterial spectrum.
 - B. To decrease bacterial resistance.
 - C. To improve the taste.
 - D. To minimize toxic effects.
 
Correct answer: B
Rationale: The correct answer is B: To decrease bacterial resistance. Trimethoprim-sulfamethoxazole (TMP-SMX) is a combination drug used to prevent bacterial resistance to sulfonamides. It works by targeting different steps in the bacterial metabolic pathway, making it harder for bacteria to develop resistance. Choice A is incorrect because the combination does not broaden the antibacterial spectrum; instead, it enhances effectiveness against specific bacteria. Choice C is incorrect as taste improvement is not the primary reason for combining these drugs. Choice D is incorrect because while combination therapy can sometimes help minimize toxic effects, the primary purpose in this case is to address bacterial resistance.
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