HESI RN
Biology Practice Test
1. In meiosis, the chromosome number is reduced from:
- A. 46 to 23
- B. 46 to 33
- C. 28 to 14
- D. 24 to 12
Correct answer: A
Rationale: The correct answer is A: "46 to 23." In meiosis, the chromosome number is reduced by half to form gametes for sexual reproduction. In humans, where the diploid chromosome number is 46, meiosis results in haploid cells with 23 chromosomes. Choices B, C, and D are incorrect because they do not represent the correct reduction in chromosome number during meiosis.
2. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
3. What is located on the rough endoplasmic reticulum?
- A. Microvilli
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: D
Rationale: The rough endoplasmic reticulum is studded with ribosomes, which are responsible for protein synthesis. Ribosomes are the correct answer because they are the organelles directly associated with the rough endoplasmic reticulum. Microvilli (choice A), mitochondria (choice B), and lysosomes (choice C) are not typically located on the rough endoplasmic reticulum. Microvilli are found on the surface of cells to increase surface area, mitochondria are the powerhouses of the cell responsible for energy production, and lysosomes are membrane-bound organelles containing digestive enzymes.
4. Which of the following is not found in a prokaryotic cell?
- A. Plasma membrane
- B. Cytoplasm
- C. Nucleus
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C, 'Nucleus.' Prokaryotic cells do not have a defined nucleus, unlike eukaryotic cells. The plasma membrane, cytoplasm, and ribosomes are all components found in prokaryotic cells. The plasma membrane surrounds the cell and regulates what enters and exits, the cytoplasm is the gel-like substance that fills the cell, and ribosomes are responsible for protein synthesis.
5. The term pleiotropy is best defined as which of the following?
- A. A situation in which one gene remains unexpressed
- B. One gene influencing multiple, seemingly unrelated phenotypic traits
- C. Two genes affected by a single allele
- D. A condition in which multiple genes are missing
Correct answer: B
Rationale: Pleiotropy is best defined as one gene influencing multiple, seemingly unrelated phenotypic traits. This phenomenon showcases the multifunctionality of genes, where a single gene can have effects on various aspects of an organism's phenotype. Choices A, C, and D do not accurately capture the concept of pleiotropy. Option A refers to gene expression, not pleiotropy. Option C describes genetic interactions but not in the context of pleiotropy. Option D talks about missing genes, which is unrelated to the definition of pleiotropy.
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