HESI RN
Biology Practice Test
1. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
2. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
3. Which of the following options correctly lists the five stages of mitosis in order from beginning to end?
- A. Prophase, Prometaphase, Telophase, Metaphase, Anaphase
- B. Prophase, Prometaphase, Metaphase, Anaphase, Telophase
- C. Metaphase, Anaphase, Prophase, Prometaphase, Telophase
- D. Metaphase, Telophase, Anaphase, Prophase, Prometaphase
Correct answer: B
Rationale: The correct order of the stages of mitosis is Prophase, Prometaphase, Metaphase, Anaphase, and Telophase. Choice A is incorrect because it has Anaphase and Metaphase in the wrong order. Choice C is incorrect as it starts with Metaphase, which is not the first stage of mitosis. Choice D is incorrect as it also has the stages in the wrong order, and it starts with Metaphase, which is incorrect.
4. Which of the following molecules contains the code required for replication?
- A. Deoxyribonucleic acid (DNA)
- B. Transfer RNA (tRNA)
- C. Messenger RNA (mRNA)
- D. Ribonucleic acid (RNA)
Correct answer: A
Rationale: The correct answer is A: Deoxyribonucleic acid (DNA). DNA contains the genetic information essential for replication, ensuring the accurate transmission of genetic material from one generation to the next. Choice B, Transfer RNA (tRNA), is involved in protein synthesis, not replication. Choice C, Messenger RNA (mRNA), carries genetic information from DNA to the ribosome but does not contain the code for replication. Choice D, Ribonucleic acid (RNA), is a broader category that includes both mRNA and tRNA, but the specific molecule containing the code required for replication is DNA.
5. What is considered the main objective of the translation stage of protein synthesis?
- A. To produce amino acids
- B. To produce nucleotides
- C. To produce fatty acids
- D. To produce nucleic acids
Correct answer: A
Rationale: The correct answer is A: To produce amino acids. During the translation stage of protein synthesis, the mRNA is decoded to assemble a specific sequence of amino acids. These amino acids then fold into a functional protein. Choices B, C, and D are incorrect because the translation stage specifically deals with the production of amino acids, not nucleotides, fatty acids, or nucleic acids.
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