HESI RN
Biology Test
1. In DNA, the nucleotide base adenine always binds with which of the following?
- A. Guanine
- B. Uracil
- C. Thymine
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Thymine. In DNA, adenine always pairs with thymine, forming a base pair held together by hydrogen bonds. Guanine pairs with cytosine. Uracil is found in RNA, not DNA. Cytosine pairs with guanine. Therefore, option C is the correct pairing for adenine in DNA.
2. Which of the following organelles is the site of cellular respiration?
- A. Nucleus
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: B
Rationale: The correct answer is B: Mitochondria. Mitochondria are known as the powerhouse of the cell because they generate most of the cell's supply of ATP through cellular respiration. The other organelles listed, such as the nucleus (choice A), lysosomes (choice C), and ribosomes (choice D), do not play a direct role in cellular respiration. The nucleus contains genetic material, lysosomes are involved in digestion and waste removal, and ribosomes are responsible for protein synthesis.
3. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
4. Which of the following correctly identifies the two types of cells?
- A. Mitosis and meiosis
- B. Mitochondrion and chloroplast
- C. Genotype and phenotype
- D. Prokaryotic and eukaryotic
Correct answer: D
Rationale: The correct answer is D: Prokaryotic and eukaryotic. Cells are classified into two major types: prokaryotic, which lack a nucleus, and eukaryotic, which have a defined nucleus and other membrane-bound organelles. Choice A, mitosis and meiosis, refers to cell division processes. Choice B, mitochondrion and chloroplast, are cell organelles involved in energy production and photosynthesis, respectively. Choice C, genotype and phenotype, relate to genetic characteristics and physical traits, not cell types.
5. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
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